(Senior) Research Technician In Vivo
Leiden Bio Science Park - Leiden
Offer As an employer, we are a true believer of the value of a workforce in which people from diverse backgrounds are encouraged to develop themselves, personally and professionally. We believe that - Volledige vacature bekijken
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Research Technician
Leiden Bio Science Park - 16-02-2025
Naar vacature
About your company We have developed an improved Monocyte Activation Test (MAT) for pyrogen testing. The MAT serves as the replacement for the Rabbit Pyrogen Test and can be used […]
About your company
We have developed an improved Monocyte Activation Test (MAT) for pyrogen testing. The MAT serves as the replacement for the Rabbit Pyrogen Test and can be used to test parenteral drugs for endotoxin and non-endotoxin contaminations. Our technology uses cryopreserved pooled PBMC. This has made it possible to develop a MAT with both high sensitivity and robustness, ensuring reliability in the field.Monocyte Activation Test (MAT)
The Monocyte Activation Test (MAT) is a pyrogen test. MAT uses human blood cells to test for a fever reaction, mimicking the human immune reaction. The MAT serves as the replacement for the Rabbit Pyrogen Test and can be used to test parenteral drugs for endotoxin and non-endotoxin contaminations. Our technology uses cryopreserved pooled PBMC. This has made it possible to develop a MAT with both high sensitivity and robustness, ensuring reliability in the field. The MAT kit includes all the required consumables to perform the Monocyte Activation Test, making it convenient to perform. In addition to the kit we provide consulting services and technical support in setting up the MAT in your organisation.
Job description
MAT Research is a pioneering company in the field of pyrogen testing, committed to ushering in a new era of ethical and accurate diagnostics. Since 2016, we have been leading the development of the Monocyte Activation Test (MAT), an animal-free alternative to traditional Rabbit Pyrogen Tests. Our ready-to-use MAT kits offer a robust and highly reliable method for detecting a broad range of pyrogens in parenteral drugs. ISO:9001:2015 certified, we uphold the highest standards of quality in all our products and services. By focusing on in-vitro human-based testing, we aim to drastically increase patient safety while saving hundreds of thousands of animal lives each year. We are steadfast supporters of the European Pharmacopoeia’s vision to replace animal-based tests with MAT by 2026. For more details, go to our job page.We are looking for an experienced Research Technician who ensures the quality and execution of lab work for product delivery and scientific research.
Your key responsibilities will include:
- Lab execution for Research and Manufacturing
- Equipment Maintenance
- Quality Assurance & Control
- Regulatory Compliance
- Data Collection & Analysis
- Documentation & Reporting
- To fulfill these responsibilities, you will:
- Execute high-precision experiments for the development of in vitro pyrogen tests using MAT and ELISA assay methods and data analysis tools.
- Data collection, processing, and (validation) report writing.
- Maintain strict QA/QC standards, upholding impeccable quality in all lab activities according to Good Laboratory Practice (GLP) quality requirements.
- Maintain meticulous experiment records, ensuring unassailable data integrity.
- Synthesize lab data into comprehensive reports, offering actionable insights on efficiency and performance.
- Inventory and logistics, optimizing stock levels through data-driven strategies and supplier relations.
- Handle day-to-day lab maintenance and admin tasks, ensuring smooth, efficient operations.
- Monitor equipment performance and data reporting under ISO9001 standards
Job requirements
- Living near Leiden or able to relocate without support.
- Bachelor’s (HLO/HBO) or Master’s (University) degree in biological/medical sciences or equivalent, preferably with a strong immunology/cellular background.
- At least 2 years of hands-on experience in chemical/biological labs, PBMC isolations, cellular assays, and analytical-based assays (ELISA, Flow Cytometry) according to regulatory standards such as ICH is a pre.
- Comfortable with data analysis software, data analysis and the thorough review of the data generated by others.
- Demonstrated finesse in experimental execution, marked by precision and meticulous attention to detail.
- Comfortable with inventory and logistics software, capable of managing resources efficiently.
- Excellent skills in technical writing and reporting.
- Experience in working under quality standards such as GLP, GMP and ISO:9001
- Self-starter with teamwork skills, adept at juggling priorities to nail deadlines.
- Fluent in English
- proficiency in Dutch, German, or French is a major plus.
- Willing to hit the road for occasional business trips.
- Experience in a pharmaceutical or biotech company is a bonus.
Your compensation will be:
- €29k-€49k/year (Full-time, 40 hrs/week)
- Twenty-five vacation days per year and your National Holidays off.
Link to vacancy
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